The TCF7L2rs7903146 polymorphism, dietary intakes and type 2 diabetes risk in an Algerian population
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منابع مشابه
Single-nucleotide polymorphism of rs11061971 (+219 A>T) in adiponectin receptor 2 (AdipoR2) gene and its association with risk of type 2 diabetes among an Iranian population
Background and Objectives: Genetic modifications in the adiponectin receptor 2 (AdipoR2) gene can affect phenotypes associated with insulin resistance and diabetes. The purpose of this study was to evaluate the possible role of genetic modifications in the AdipoR2 gene, to determine the frequency of genotypes and polymorphism alleles of this gene at rs11061971 (+219 A>T), and to investigate its...
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Background and Objectives: Adiponectin is an adipokine, which is abundantly expressed in adipose tissue and has a potent roles in insulin sensitivity. This study aimed to test the association of single nucleotide polymorphism of rs1501299 of the adiponectin gene with adiponectin levels and type 2 diabetes. Methods: This case-control study was conducted on 80 diabetic patients with fasting bl...
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Background: Diabetes is one of the most common chronic metabolic diseases in the world that is caused by decreased insulin secretion or insulin resistance and fat accumulation in visceral adipose tissue (IR). Omentin is a protein inferred from adipose tissue that is associated with the rate of diabetes. The aim of this study was to investigate the relationship between rs2274907 polymorphism of ...
متن کاملDietary Phylloquinone and Menaquinones Intakes and Risk of Type 2 Diabetes
OBJECTIVE To investigate whether dietary phylloquinone and menaquinones intakes are related to risk of type 2 diabetes. RESEARCH DESIGN AND METHODS We used data from a prospective cohort study in 38,094 Dutch men and women, aged 20-70 years. Dietary phylloquinone and menaquinones intakes were assessed using a validated food frequency questionnaire. Diabetes case patients were ascertained main...
متن کاملThe Soluble Carrier 30 A8 (SLC30A8) Gene Polymorphism and Risk of Diabetes Mellitus Type 2 in Eastern Azerbijan Population of Iran
Type 2 Diabetes Mellitus (T2D) is the most common metabolic disease demonstrating itself by hyper- glycemia, due to impaired insulin secretion or action. Recently, Whole-Genome Association studies have revealed the role of several new genes responsible for T2D. One of the most studied genes is SLC30A8 (Zn-T8) which is exclusively expressed in pancreatic ?-cells and participates in insulin stora...
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ژورنال
عنوان ژورنال: BMC Genetics
سال: 2014
ISSN: 1471-2156
DOI: 10.1186/s12863-014-0134-3